Ticagrelor STADA together with acetylsalicylic acid (another antiplatelet medicine) is indicated for use in adults only. You have been given this medicine because you have:
• a myocardial infarction more than a year ago.
• unstable angina (angina or chest pain that is not well controlled)
The medicine reduces the risk of having another heart attack, stroke or dying from related heart or blood vessel damage.

How does Ticagrelor STADA work:
Ticagrelor STADA affects cells called ‘platelets’ (also called thrombocytes). These very small cells in the blood help to stop bleeding by sticking together (aggregating) to plug small holes in cut or damaged blood vessels.
However, platelets can also form clots inside diseased blood vessels in the heart and brain. This can be very dangerous because:
• the clot may completely block the blood supply – this can cause a heart attack or stroke, or
• the clot can partially block the blood vessels that supply the heart – this reduces blood flow
• to the heart and can cause chest pain that comes and goes (called “unstable angina”).
Ticagrelor STADA helps to stop platelets from clumping together. This reduces the risk of a blood clot forming which can reduce blood flow.

Do not take Ticagrelor STADA if:
• You are allergic to ticagrelor or any of the other ingredients of this medicine.

Talk to your doctor or pharmacist before taking Ticagrelor STADA.

Pregnancy and breastfeeding:
This medicine is not recommended for use if you are pregnant or may become pregnant. Women should use adequate contraception to avoid pregnancy while taking this medicine.

Talk to your doctor before taking Ticagrelor STADA if you are breast-feeding. Your doctor will discuss with you the benefits and risks of taking Ticagrelor STADA during this period.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to become pregnant, ask your doctor or pharmacist for advice before taking this medicine.

Driving and using machines:
Ticagrelor STADA is unlikely to affect your ability to drive or use machines. If you feel dizzy or confused while taking this medicine, be careful when driving or using machines.

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
Dosage:
• The usual dose is two 90 mg tablets at the same time (loading dose of 180 mg).

This dose will usually be given to you in hospital.
• After this initial dose, the usual dose is one 90 mg tablet twice a day for up to 12 months, unless your doctor tells you otherwise.
• Take this medicine at about the same time each day (for example, one tablet in the morning and one in the evening).
Treatment with Ticagrelor STADA together with other blood clotting medicines
Your doctor will also tell you to take acetylsalicylic acid. This is a substance found in many medicines used to prevent blood clots. Your doctor will tell you how much to take (usually between 75-150 mg daily).

How to take Ticagrelor STADA:
• You can take the tablet with or without food.
If you have difficulty swallowing the tablet(s)
If you have difficulty swallowing the tablet, you can crush it and mix it with water, as described above.
down:
• Crush the tablet until you get a fine powder
• Put the powder in half a glass of water
• Stir and drink immediately
• To make sure there is no unused medicine left, rinse the empty glass with another half glass of water and drink the contents.
• If you are in hospital, you may be given this tablet mixed with water through a tube
inserted into the nose (nasogastric tube).

Medicines sold in pharmacies / for patients only - to be deleted if not applicable:
Instructions for opening the bottle
Press down on the cap and turn it counterclockwise.

If you have any further questions on this medicine, ask your doctor or pharmacist.

- The active substance is ticagrelor. Each film-coated tablet contains 90 mg of ticagrelor.
- The other components are
Core: mannitol, calcium hydrogen phosphate dihydrate, hydroxypropyl cellulose, carmellose calcium, magnesium stearate 90 mg
Tablet film coating: hypromellose (E 464), titanium dioxide (E 171), talc (E 553b), yellow iron oxide (E 172), macrogol (E 1521).

Warning:
Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

56 film-coated tablets