Ostenil, 20mg/2ml hyaluronic acid injectable solution for infiltration, 1 pre-filled syringe, TRB Chemedica

Ostenil, 20mg/2ml injectable solution with hyaluronic acid for infiltrations, 1 prefilled syringe, TRB Chemedica

Properties:
Ostenil 20mg/2ml injection is used to treat pain caused by osteoarthritis (OA) of the knee in people who have already tried pain medicines (eg paracetamol) and other therapies that have failed.

Ostenil 20mg/2ml is identical to a chemical found naturally in the joints. It helps the joints function properly by serving as a lubricant and shock absorber in the joints.
Ostenil 20mg/2ml should only be administered by or under the direct supervision of a physician.

Hyaluronic acid and visco-supplementation
Osteoarthritis is a joint condition that is degenerative. Cartilage degradation is a defining feature of this condition. Various changes occur, including those of the quality of the synovial fluid, which loses its viscoelasticity. It can no longer properly perform its functions of lubrication and cushioning, which are essential for the functioning of the joint. Arthritic pain occurs, movements become more difficult, and mobility may be reduced.

Hyaluronic acid is a naturally occurring substance in synovial fluid. It is essential to maintain the quality of the synovial fluid for it to remain effective. It is much more necessary in highly stressed joints such as those that bear a lot of weight, such as the knee.

Composition:
Active ingredient: 1 ml of isotonic solution contains 10 mg of sodium hyaluronate, as well as sodium chloride, disodium phosphate, monosodium phosphate and water for injections.
The hyaluronic acid in Ostenil ® is produced by bacterial fermentation and is highly purified, no animal protein is present.

Precautions:

If the package has been opened or is damaged, do not use Ostenil 20mg/2ml®. Store at temperatures below 25° C in the original packaging (away from light, heat and frost)

An aseptic approach must be observed during administration.

As Ostenil 20mg/2ml may precipitate in the presence of disinfectants containing quaternary ammonium salts, do not use them at the same time for skin disinfection.

Before injecting Ostenil 20mg/2ml®, administer subcutaneous lidocaine or a comparable local anesthetic.

Before injecting Ostenil 20mg/2ml®, remove any joint effusion that may be present.

When removing joint effusion and injecting Ostenil 20mg/2ml®, do not use the same syringe.

Carefully remove the syringe cap and needle aseptically.

Using a 20-gauge needle, inject Ostenil 20mg/2ml® into the joint.

The vial/syringe is designed for single use only. Once the container has been opened, the contents of the vial should be used immediately. Any unused amount of Ostenil 20mg/2ml® must be thrown away. Only inject the entire 2 ml amount into one knee. If the therapy is bilateral, each knee should be treated with its own vial.

Contraindications:
Patients with a history of hypersensitivity to any of the components should avoid using Ostenil ® .

Possible negative effects:
Pain, heat, redness and edema may occur in the joint treated with Ostenil ® . Applying an ice pack to the affected area for 5 to 10 minutes will help lessen these side effects.

Interactions with other drugs:
There is currently no information on the incompatibility of Ostenil ® with other intra-articular solutions. Administration of analgesics or anti-inflammatory drugs at the same time during the first days of treatment may be beneficial for the patient.

Presentation:
1 pre-filled syringe